Brandon Aiyuk is facing a challenging matchup against the secondary of the Kansas City defense. The Chiefs have been strong in their pass defense this season and currently rank fourth-best in the NFL by allowing only 176.5 passing yards per game. Additionally, they have allowed only 17.3 points per game which is the second-best in the league.

Brandon Aiyuk had his best season as a pro, recording 1,342 receiving yards, 75 receptions, and 7 touchdowns this year.

The 49ers will need Aiyuk to win at the line of scrimmage with his elite route-routing ability on one of the biggest stages of his young NFL career.